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Ashwagandha and Stress Reduction

Ashwagandha, scientifically known as Withania somnifera and also referred to as Indian Ginseng or Winter Cherry, has been esteemed for its nootropic benefits for millennia within the framework of Ayurvedic medicine.

This ancient herb is not just a cornerstone of traditional healing practices but has also captured the attention of modern science due to its potential cognitive and stress-relief benefits.

This blog will review the specifics of a recent scientific publication that explores Ashwagandha's efficacy as a nootropic, offering a fresh perspective on its adaptogenic properties and implications for cognitive enhancement.



  • Background
  • Study Overview
  • Results
  • Discussion


Ashwagandha and Stress Reduction


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Historically, Ashwagandha has been a staple in Ayurvedic medicine for over six thousand years, known for its rejuvenate and restorative benefits.

Traditionally used by various cultures, Ashwagandha's roots were believed to impart the strength and vigour of a horse, reflecting the herb’s profound impact on physical and mental health.

Today, it is celebrated not only for its therapeutic uses but also for its role in enhancing mental acuity and managing stress—a reflection of its adaptogenic qualities.

The general benefits of Ashwagandha are wide-ranging, encompassing improved mental clarity, increased energy, and better stress management. As a nootropic, it has garnered acclaim for its ability to stabilize mood and enhance cognitive functions, including memory and concentration, making it an invaluable supplement in the fast-paced, stress-filled modern world.


Study Overview

The study titled "A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults" was conducted by K. Chandrasekhar, Jyoti Kapoor, and Sridhar Anishetty, and published in the Indian Journal of Psychological Medicine in July-September 2012.

The research aimed to examine the safety and effectiveness of a high-concentration full-spectrum Ashwagandha root extract in alleviating stress and anxiety while improving the general well-being of adults under chronic stress.

This double-blind, placebo-controlled trial involved 64 subjects with a history of chronic stress.

Participants were randomized into two groups: one receiving the Ashwagandha extract and the other a placebo. Each participant took one capsule twice a day for a duration of 60 days. The study monitored compliance and any adverse reactions through regular follow-up calls and final evaluations were conducted at the end of the study period.




The study unveiled that the group receiving the Ashwagandha root extract exhibited significant reductions in stress assessment scores and serum cortisol levels compared to the placebo group.

On Day 60, the treatment group showed a remarkable decrease in the scores on all stress-assessment scales, with the serum cortisol levels also substantially reduced, highlighting the extract’s potent stress-relieving effects.

Statistical analysis confirmed the significance of these findings, with P-values less than 0.0001 for stress-assessment scales and 0.0006 for cortisol reductions.

These results provide compelling evidence of Ashwagandha’s efficacy as a natural adaptogen, offering a promising alternative for managing stress and enhancing well-being in adults facing chronic stress.



The results of the study reinforce the reputation of Ashwagandha as a powerful adaptogen, capable of significantly reducing stress and anxiety levels.

This aligns with traditional Ayurvedic practices that have championed Ashwagandha for its holistic benefits to both mind and body health.

The significant reductions in serum cortisol and stress-assessment scores not only corroborate historical claims but also provide a scientific foundation for its therapeutic use.

Future research could expand on these results by including a more diverse demographic over a longer period to explore the long-term effects and potential side effects of Ashwagandha supplementation.

Practically, the findings suggest that incorporating Ashwagandha into daily routines could be beneficial for individuals experiencing chronic stress, improving their overall mental health and resilience. For those interested in natural remedies for stress and cognitive enhancement, Ashwagandha offers a promising option.



This study confirms Ashwagandha's efficacy in reducing stress and anxiety, providing a solid scientific basis for its traditional use as a rejuvenative and stress-relief nootropic.

Its ability to significantly lower cortisol levels and improve stress scores makes it a valuable supplement for enhancing mental wellness.


Learn more about the vitamins, minerals and natural nootropic plant extracts we use to give your brain a daily boost 

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